Charles Hamilton Eglee grew up in North Haven, Connecticut and Eastham, Massachusetts. He graduated Cum Laude from Williston Academy and received his B.A. in English from Yale College. After a brief sting teaching film History at Yale, Eglee moved to California and worked for Roger Corman, where he served in a variety of production capacities and struck up a friendship with then production designer, James Cameron. With Cameron, Eglee wrote the immortal Piranha II: The Spawning.

In 1984, Eglee joined the writing staff of St. Elsewhere as Story Editor. During his tenure, his work was nominated for an Emmy Award and Humanitas Prize. He went on to become writer and Supervising Producer of the ABC series Moonlighting, where he was, once again, nominated for an Emmy Award.

Joining Steven Bochco Production in 1991, Eglee wrote and co-executive produced Civil Wars for two seasons, during which time he also shouldered writing chores on L.A. Law. In 1994, he joined NYPD Blue during it second season as writer and Co-executive Producer and received an Emmy Award for Best Drama.

In 1995, he co-created Murder One with Steven Bochco and was the show's Executive Producer. His work was nominated for an Emmy Award, a Golden Globe, the Writer's Guild Award and he received the People's Choice Award.

Eglee and James Cameron re-teamed in 1999 to co-create Dark Angel starring Jessica Alba. Dark Angel garnered a People's Choice Award for Favorite New Television Dramatic Series and Alba was nominated for a Golden Globe Award.

Eglee is privileged to serve as a writer/executive producer on THE SHIELD in its fifth season. He now spends his days contemplating the nether world of human experience.